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نویسنده

  • H. Henrik Thomsen
چکیده

An unusual case of benign fibroepithelial polyp of the renal pelvis in a patient past middle age is presented. Peroperative frozen section microscopy should be done to prevent nephroureterectomy. The therapy was local excision. The postoperative course was uneventful. Henrik Thomsen, MD, Surgical Department P, Silkeborg Centralsygehus, DK-8600 Silkeborg (Denmark) The fibroepithelial polyp has previously been described as a ureteral lesion in younger persons [1, 2]. It is rare that this benign condition involves the renal pelvis as a solitary lesion, and it is especially remarkable to see it in a patient past middle age. Less than 20% of the tumors of the renal pelvis are benign. Williams and Niederhaeusern [3] have classified them as follows: 1 Tumors of epithelial origin (papillomas) which are potentially malignant Tumors of mesodermal origin Fibrous polyps Angiomatous polyps Hemangiomas or lymphangiomas Leiomyomas Neurofibromas Miscellaneous types; endometriosis, amyloidosis granulomas As conservative surgery rather than nephroureterectomy should be performed in this benign condition [4, 5], we have found it relevant to mention the following case. A urinalysis performed by the family physician revealed negative urine cultivation. There was no gross hematuria. 11 years previously a transvesical prostatectomy had been performed. Microscopy showed cancer of the prostatic gland and he has been treated with diethylstilbestrol ever since. He has also been treated several times for stenosis of the urethra and has received treatment for hypertension for the last 20 years. The laboratory findings were as follows: BP 160/90 mm Hg; Hb 6.5 mmol/l; leukocyte count 12.0 × 109/1; serum creatinine 340; serum electrolyte normal; acid phosphatase 5.5. Urine examination showed 8–10 erythrocytes, 1–2 leukocytes, no cylinders and a few bacteria. An excretory urogram showed no excretoric function of the left kidney and a normal pyelogram on the right side. Cystoscopy showed normal function of both ureteral ostia. A retrograde ureterogram revealed a 2 × 6 cm large mobile filling defect in the lower part of the renal pelvis (fig. 1). At operation a pyelotomy was done and a 1 × 2 X 6.5 cm large light-red smooth polyp was found attached to the lower calyx wall. Local excision was accomplished (fig. 2). Frozen section microscopy showed a fibroepithelial polyp without malignancy.The postoperative course was uneventful. D ow nl oa de d by : 54 .7 0. 40 .1 1 10 /6 /2 01 7 1: 59 :4 5 A M Final microscopic examination revealed a fibrous stroma with varying amounts of cells and only a few mitoses present. The surface was covered with normal urothelium. Case Report A 77-year-old man was admitted to the hospital for urologic examination because of intermittant left flank pain, chills and fever attacks up to 39.5 °C. Conclusion It is well known that patients with ureteral polyps present with flank pain due to obstruction of the urine flow [1, 4, 5]. Intermittent flank pain can be seen in Solitary Fibroepithelial Polyp of the Renal Pelvis 457 Fig. 1. Retrograde ureterogram showing fibroepithelial polyp in the left renal pelvis. Fig. 2. Fibroepithelial polyp from renal pelvis. patients with polyps of the renal pelvis due to partial obstruction. Hematuria can be seen in both conditions [4–6]. The pathogenesis of these benign polyps is still unknown [4, 5]. Hormonal influence, infection, obstruction and congenital origin have been proposed [2, 6]. Allergy has also been mentioned as a possibility [4]. Benign polyps are mostly present in the upper ureter and they usually occur in patients between the ages of 5 and 40 years [1, 4, 6]. The preoperative diagnosis can be difficult [5]. Radiologically they show a sharp smooth filling defect. At operation no infiltration into the surrounding tissue is seen [4]. Peroperative diagnosis is important and consequently frozen sections should be taken at least in dubious cases [5]. In the past many unnecessary nephroureterectomies were performed as a treatment for ureteral polyps D ow nl oa de d by : 54.70.40.11-10/6/20171:59:45AM [7], perhaps because these cases were mistaken for papillary carcinomas due to a lack ofknowledge of the condition [5]. The treatment is simple local excision [3]. Recurrence has neverbeen reported [5].ReferencesCompere, D.E.; Begley, G.F.; Isaacks, H.E.; Frazier, T.H.; Dry-den, D.B.: Ureteral polyps. J.Urol. 79: 209–214 (1958).Evans, A.T.; Stevens, R.K.: Fibroepithelial polyps of ureter and renal pelvis, a case report. J.Urol. 86: 313–335 (1961).Williams, D.L; Niederhaeusem, W.V.: Les polypes de Γuretère. J. Urol. Néphrol. 69: 145–154(1963).Jansen, T.T.H.; Van De Weyer, F.P.H.; Devries, H.R.: Angio-matous ureteral polyp. Urology 30:426–427 (1982).Olsen, S.: Tumors of the kidney and urinary tract, p. 146 (Munksgaard, Kopenhagen 1984).Debruyne, F.M.J.; Moonen, W.A.; Daenekindt, A.A.; Delaere, K.P.M.: Fibroepithelial polyp ofureter. Urology 16: 355–359 (1980).Melicow, M.M.; Findlay, H.V.: Primary benign tumors of the ureter. Surgery Gynec. Obstet. 54:680–689 (1932). Downloadedby: 54.70.40.11-10/6/20171:59:45AM

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تاریخ انتشار 2009